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Antihistamines can help to reduce the bodys reaction to the injection
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Favorable reductions in ROS levels were restricted to the hippocampus, posterior cortex, and cerebellum, whereas other brain regions showed heterogeneous or unfavorable redox responses, including alterations in antioxidant enzyme activity
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MDMA administration led to significant elevations in MDA and 8-OHdG, reductions in antioxidant enzymes (GPx, GST, GSH, SOD), upregulation of inflammatory mediators (MPO, NF-B, TNF-), and disruption of ion homeostasis via altered Na/K ATPase and Ca ATPase activities
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